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Description

2017;12:e0180953

The bottom line Run the same seven checks on both compounds and they diverge on six of them and match on the seventh, unsupervised sourcing risk, where theyre equally exposed

Side effects and safety considerations Most side effects are mild

APAP@PEG/HMnO 2 combined with ROS induced by cytotoxic benzoquinone metabolites and GSH depletion caused by HMnO 2 amplified the efficacy of chemotherapy by increasing intratumoral oxidative stress, leading to cell death in vitro as well as tumor suppression in vivo and increasing the survival rate [166]